| 產(chǎn)品名稱 |
Canine parvovirus |
| 商品貨號 |
B162756 |
| Classification |
Parvoviridae, Parvovirus, Feline panleukopenia virus |
| Agent |
Canine parvovirus |
| Strain |
CPV 6C2B23 |
| Applications |
in another host, produces protein capsid protein |
| Biosafety Level |
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Isolation |
Nuclear polyhedrosis virus Autographa californica with canine parvovirus gene inserted |
| Product Format |
frozen |
| Storage Conditions |
4°C or gas phase of liquid nitrogen freezer |
| Disclosure |
This material is cited in a US or other Patent and may not be used to
infringe the claims. Depending on the wishes of the Depositor, ATCC may be
required to inform the Patent Depositor of the party to which the material was
furnished. This material may not have been produced or characterized by ATCC. |
| Comments |
Recombinant baculovirus contains a canine parvovirus gene coding for the production of VP-2 capsid protein. The CPV VP-2 protein is expressed when the virus is propagated in insect cells. The recombinant virus does NOT induce polyhedra in infected cells. Recombinant baculovirus incorporating sequences from pAc 6C2B23 (ATCC 67682). Lacks polyhedrin production but produces immunogenic VP-2 which can protect canines against challenge with virulent canine parvovirus. |
| Effect on Host |
Yes, in vitro effects: Swelling of nuclei, cells round up and cell membrane appears wrinkled |
| Name of Depositor |
Cornell Univ., RW Hardy, Cornell Univ. |
| U.S. Patent |
|
| U.S. Patent Number |
|
| Source |
Nuclear polyhedrosis virus Autographa californica with canine parvovirus gene inserted |
| References |
Wood HA, Parrish CR. Subunit canine parvovirus vaccine. US Patent 4,971,793 dated Nov 20 1990
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