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<em>Cunninghamella elegans</em> Lendner
<em>Cunninghamella elegans</em> Lendner
規格:
貨期:
編號:B170843
品牌:Mingzhoubio

標準菌株
定量菌液
DNA
RNA

規格:
凍干粉
斜面
甘油
平板


產品名稱 Cunninghamella elegans Lendner
商品貨號 B170843
Deposited As Cunninghamella blakesleeana Lendner
Strain Designations NRRL 1369 [DSM 1906, IMI 53585, IMI 63877]
Application
oxidizes ebastine
produces 1',2'-dihydro-1',2'-dihydroxyrotenone
produces 1,2-dihydrorotenone
produces 3'-hydroxyrotenone
produces acronine acronycine
produces imipramine
transforms alkaloids
transforms flavonoids
transforms pergolide
oxidation of ebastine to carebastine
transformation of sesquiterpene lactone costunolide
transformation of: pergolide to pergolide sulfoxide
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format frozen
Storage Conditions Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Type Strain no
Preceptrol&reg; no
Mating Type mating type plus
Comments
Comparable to Upjohn H-334 used in oxidation of steroids
Medium ATCC® Medium 200: YM agar or YM broth
ATCC® Medium 307: Cornmeal agar
ATCC® Medium 336: Potato dextrose agar (PDA)
Growth Conditions
Temperature: 24°C to 26°C
Atmosphere: Typical aerobic
Name of Depositor NRRL
Special Collection NSF - Mycology
References

Sariaslani FS, Rosazza JP. Microbial transformations of natural antitumor agents: Products of rotenone and dihydrorotenone transformation by Cunninghamella blakesleeana. Appl. Environ. Microbiol. 45: 616-621, 1983.

Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of flavone and isoflavone. Xenobiotica 20: 363-373, 1990. PubMed: 2346033

Mann KM, et al. Studies on microbiological oxidation of steroids by Cunninghamella blakesleeana. Effect of alcohols and phenol. Appl Microbiol 3: 14, 1955.

Schwartz H, et al. Microbial oxidation of ebastine. Appl. Microbiol. Biotechnol. 44: 731-735, 1996. PubMed: 8867630

Betts RE, et al. Microbial transformations of antitumor compounds. I. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata. J. Med. Chem. 17: 599-602, 1974. PubMed: 4829940

Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979.

Hufford CD, et al. Metabolism of imipramine by microorganisms. J. Pharm. Sci. 70: 151-155, 1981. PubMed: 7205217

Reighard JB, et al. Microbial biotransformations. I. O-Demethylation of 7,8-dimethoxy-2-methyl-1-(4'-methoxybenzyl) 1,2,3,4.-tetrahydroisoquinoline by Cunninghamella blakesleeana. J. Nat. Prod. 44: 466-469, 1981.

Smith RV, et al. Microbial transformations of pergolide to pergolide sulfoxide and pergolide sulfone. J. Pharm. Sci. 72: 733-736, 1983. PubMed: 6684155

梅經理 17280875617 1438578920
胡經理 13345964880 2438244627
周經理 17757487661 1296385441
于經理 18067160830 2088210172
沈經理 19548299266 2662369050
李經理 13626845108 972239479
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