In sM produces dengeneration of muscle with loss of striation and hyaline changes.
In sM produces dengeneration of muscle with loss of striation and hyaline changes.
Biosafety Level
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Isolation
feces from 2-year-old female, South Africa, 1950
Product Format
frozen
Storage Conditions
? -60°C
Comments
Plaques containing rounded or dendritic cells with granular cytoplasm appear in secondary HAm cell cultures in 3 days and the CPE is maximal on the 7th day. In sM produces dengeneration of muscle with loss of striation and hyaline changes.
Plaques containing rounded or dendritic cells with granular cytoplasm appear in secondary HAm cell cultures in 3 days and the CPE is maximal on the 7th day. In sM produces dengeneration of muscle with loss of striation and hyaline changes.
Effect on Host
Yes, in vitro effects: Cytopathic effects in tissue culture
CPE (TC), death (sM)
Yes, in vivo effects: death in suckling mice
Recommended Host
human amnion cells; suckling mouse, i.p. inoculation for mouse passage
Host of Choice:? HAm (TC), sM? (i.p.) for M passage
Host Range: HAm, HED, HeLa cells (TC), sM (mouse passage)
human amnion; human embryonic diploid cells; HeLa cells (ATCC CCL-2); suckling mouse
Growth Conditions
Duration: 3-7 days
Name of Depositor
HA Wenner, H Plager
Source
feces from 2-year-old female, South Africa, 1950
Year of Origin
1950
References
Sickles GM, et al. Recently classified types of Coxsackie virus, group A; behavior in tissue culture. Proc. Soc. Exp. Biol. Med. 90: 529-531, 1955. PubMed: 13273503
Gear JH. Poliomyelitis. Papers and discussions presented at the Second International Poliomyelitis Conference. Philadelphia, PA: Lippincott; 1952.