| Insert |
DNA: genomic Insert lengths(kb): 15.5 Tissue: liver Gene product: DNA Segment, single copy [D5S61] Alleles: B1, A1, A2, A3, A4, B2 |
| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--20.0, 12.0 (doublet), 3.5; HindIII-->23.0, 6.0, 4.2, 2.2, 1.7, 1.4; KpnI-->23.0, 1.4; SacI-->23.0, 6.8, 5.8, 3.6, 2.3; SmaI-->23.0, 7.6. Enzyme(s) not detecting polymorphism: EcoRI, BamHI, XbaI, BglII, HincII, PvuII, SacI (panel of 5 individuals). |
| References |
Schumm JW, et al. Identification of more than 500 RFLPs by screening random genomic clones. Am. J. Hum. Genet. 42: 143-159, 1988. PubMed: 2892396
Donis-Keller H, et al. A genetic linkage map of the huma genome. Cell 51: 319-337, 1987. PubMed: 3664638
Kazazian HH Jr., et al. Characterization of a spontaneous mutation to a B-thalassemia allele. Am. J. Hum. Genet. 38: 860-867, 1986. PubMed: 3014870
Jacobsen SJ, et al. A clinically homogeneous group of families with facioscapulohumeral (Landouzy-Dejerine) muscular dystrophy: linkage analysis of six autosomes. Am. J. Hum. Genet. 47: 376-388, 1990. PubMed: 1975474
Hastbacka J, et al. Diastrophic dysplasia gene maps to the distal long arm of chromosome 5. Proc. Natl. Acad. Sci. USA 87: 8056-8059, 1990. PubMed: 1978318
Weiffenbach B, et al. A genetic linkage map of human chromosome 5 with 60 RFLP loci. Genomics 10: 173-185, 1991. PubMed: 1675192
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