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pUC10-41 [pA10-41]
pUC10-41 [pA10-41]
規格:
貨期:
編號:B175723
品牌:Mingzhoubio

標準菌株
定量菌液
DNA
RNA

規格:
凍干粉
斜面
甘油
平板


產品名稱 pUC10-41 [pA10-41]
商品貨號 B175723
Designations pUC10-41 [pA10-41]
Species Homo sapiens, human
Vector
Construct size (kb): 3.099999904632568
Insert
DNA: genomic
Insert lengths(kb): 0.3449999988079071
Gene product: DNA Segment, single copy [D17S71]
Alleles: B2, A1, A2, B1
Insert Size (kb) 0.345
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Shipping Information Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng)
Comments
Constructed by recloning the insert from pABL10-41 along with some of the original piVX (the multiple-cloning sequence) into the EcoRI site.
Restriction digests of the clone give the following sizes (kb): EcoRI--2.7, 0.4; HindIII--2.7, 0.4; BamHI--3.1; SalI--3.1; PstI--3.1.
Linked to von Recklinghausen neurofibromatosis (NF1), theta max = 0.1, LOD score = 16.9.
Detects the same polymorphism as pABL10-41 (aka A10-41).
Combined heterozygosity with MspI and PvuII RFLPs is about 50%.
References

Baker SJ, et al. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 244: 217-221, 1989. PubMed: 2649981

Timmerman V, et al. Assignment of the Charcot-Marie-Tooth neuropathy type I (CMT Ia) gene to 17p11.2-p12. Am. J. Hum. Genet. 47: 680-685, 1990. PubMed: 2220808

Barker D, et al. Gene for von Recklinghausen neurofibromatosis is in the pericentromeric region of chromosome 17. Science 236: 1100-1102, 1987. PubMed: 3107130

White R, et al. Tightly linked markers for the neurofibromatosis type 1 gene. Genomics 1: 364-367, 1987. PubMed: 2896632

Skolnick MH, et al. Linkage of NF1 to 12 chromosome 17 markers: a summary of eight concurrent reports. Genomics 1: 382-383, 1987. PubMed: 2896634

David F Barker, personal communication

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