| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--8.2, 3.2; HindIII--11.0; BamHI--7.2, 2.0, 1.9; PvuII--4.0, 3.2, 2.6, 0.78; PstI--4.4, 2.8, 2.6, 0.35, 0.30, 0.26. Restriction digests of the plasmid give the following sizes (kb): EcoRI--8.8, 2.95; HindIII--11.8; BamHI--6.8, 1.9, 1.8. Includes exon 1, the 5' flanking region, and a portion of intron 1. |
| References |
Poller W, et al. Cloning of the human alpha2-macroglobulin gene and detection of mutations in two functional domains: the bait region and the thiolester site. Hum. Genet. 88: 313-319, 1992. PubMed: 1370808
Faber JP, et al. The molecular basis of alpha 1-antichymotrypsin deficiency in a heterozygote with liver and lung disease. J. Hepatol. 18: 313-321, 1993. PubMed: 8228125
et al., et al. . Am. J. Hum. Genet. 49: 134, 1991.
Wolfgang Poller, personal communication
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