| Comments |
Restriction digests of the clone give the following sizes (kb): PstI--2.7, 0.62; HindIII--2.9, 0.46; EcoRI--3.4; PvuII--2.3, 0.9; BglI--2.2, 1.0. The insert contains a HindIII site, 0.45 kb from the 5' PstI site (nt 2335 of the published sequence). Detects a human genomic EcoRI fragment of 26 kb. Subcloned from pH14g. Corresponds to nucleotides 1879 to 2508 of the published sequence and is derived from intron 4. Enzyme(s) not detecting polymorphism: EcoRI, HindIII, BamHI, XbaI, SacI, TaqI, PvuII, PstI, BglII, MspI, KpnI. |
| References |
Pash J, et al. Chromosomal protein HMG-14 gene maps to the Down syndrome region of human chromosome 21 and is overexpressed in mouse trisomy 16. Proc. Natl. Acad. Sci. USA 87: 3836-3840, 1990. PubMed: 2140193
Landsman D, et al. Chromosomal protein HMG-14. Identification, characterization, and chromosomal localization of a functional gene from the large human multigene family. J. Biol. Chem. 264: 3421-3427, 1989. PubMed: 2563381
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