| Comments |
Restriction digests of the clone give the following sizes (kb): BamHI--8.3 insert + arms; EcoRI--22.0, 13.0, 7.8. Insert contains BamHI (0.33), HindIII (1.7), HindIII (4.28) sites in distance (kb) from 23.08 kb arm. Codominant segregation of the BamHI polymorphism has been demonstrated in 2 families (9 individuals). Enzyme(s) not detecting polymorphism: EcoRI, HindIII, MspI, TaqI, PstI. |
| References |
Weiffenbach B, et al. A genetic linkage map of human chromosome 5 with 60 RFLP loci. Genomics 10: 173-185, 1991. PubMed: 1675192
Sheth P, et al. Linkage analysis in spinal muscular atrophy, by six closely flanking markers on chromosome 5. Am. J. Hum. Genet. 48: 764-768, 1991. PubMed: 2014799
Dietzsch E, et al. An anonymous human single copy genomic clone, D5S6 (M4) on chromosome 5 identifies a three allele RFLP. Nucleic Acids Res. 14: 1923, 1986. PubMed: 3005988
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