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<i>Glarea lozoyensis</i> Bills et Pelaez
<i>Glarea lozoyensis</i> Bills et Pelaez
規格:
貨期:
編號:B195360
品牌:Mingzhoubio

標準菌株
定量菌液
DNA
RNA

規格:
凍干粉
斜面
甘油
平板


產品名稱 Glarea lozoyensis Bills et Pelaez
商品貨號 B195360
Deposited As Zalerion arboricola Buczacki
Strain Designations MF5171
Application
Produces antifungal agents
Produces pneumocandin complex
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format frozen
Storage Conditions Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Type Strain yes
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
Preceptrol&reg; no
Genome Sequenced Strain

Yes

Comments
Taxonomic revision
Genome sequencing strain (Institute of Microbiology, Chinese Academy of Sciences, China)
Morphology Colonies on PDA are attaining 60-62 mm diam. in 4 weeks. Mature colonies are effuse, with submerged and aerial hyphae, surface hairly, lanose, or funiculose, dull to moderately shiny; colony color is pale pinkish buff.
Medium ATCC® Medium 200: YM agar or YM broth
ATCC® Medium 336: Potato dextrose agar (PDA)
ATCC® Medium 337: Potato, dextrose, yeast agar (PDY)
Growth Conditions
Temperature: 24°C to 26°C
Atmosphere: Typical aerobic
Sequenced Data
18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence

GGTTTCCGTAGGTGAACCTGCGGAAGGATCATTACAGTGTTCCCTGCCCTCGCGGGTAGAAACGCCCACCCTTGTGTAATATATCATGTTGCTTTGGCAGGCCGCCCTCGGGCACCGGCTCCGGCCGGGTCGCGCCTGCCAGAGGACCCCAAACTCTGAATGTTAGTGTCGTCTGAGTACTATATAATAGTTAAAACTTTCAACAACGGATCTCTTGGTTCTGGCATCGATGAAGAACGCAGCGAAATGCGATAAGTAATGTGAATTGCAGAATTCAGTGAATCATCGAATCTTTGAACGCACATTGCGCCCCGTGGTATTCCGCGGGGCATGCCTGTTCGAGCGTCATTTAAACCAATCCAGCTTGCTGGGTCTTGGGCTCTCGCCTCCGGGCGGGCCTTAAAATCAGTGGCGGCGCCACCCGGCTCTAAGCGTAGTAATACTCCTCGCTACAGGGCTCCGGGTGGAGGCTGGCCAACAACCCCCAATTTTATCAGGTTGACCTCGGATCAGGTAGGGATACCCGCTGAACTTAAGCATATCAATA

Name of Depositor Merck & Co., Inc.
U.S. Patent Number
Isolation
Pond water, Valle del Rio Lozoya, Spain
Cross References

Nucleotide (GenBank) : U33266 Zalerion arboricola pyrroline carboxylate reductase (P5CR) mRNA,

Nucleotide (GenBank) : ALVE00000000 Glarea lozoyensis ATCC 20868, whole genome shotgun sequencing project

References

Shinohara C, et al. Gypsetin, a new inhibitor of acyl-CoA:cholesterol acyltransferase produced by Nannizzia gypsea var. incurvata IFO 9228. I. Fermentation, isolation, physico-chemical properties and biological activity. J. Antibiot. 47: 163-167, 1994. PubMed: 8150711

Nuber B, et al. Gypsetin, a new inhibitor of acyl-CoA:cholesterol acyltransferase produced by Nannizzia gypsea var. incurvata IFO 9228. II. Structure determination. J. Antibiot. 47: 168-172, 1994. PubMed: 8150712

Giacobbe RA, et al. Antifungal fermentation product. US Patent 4,931,352 dated Jun 5 1990

Giacobbe RA, et al. Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol. US Patent 5,021,341 dated Jun 4 1991

Masurekar PS, et al. Pneumocandins from Zalerion arboricola. II. Modification of productspectrum by mutation and medium manipulation. J. Antibiot. 45: 1867-1874, 1992. PubMed: 1490877

Schwartz RE, et al. Pneumocandins from Zalerion arboricola. I. Discovery and isolation. J. Antibiot. 45: 1853-1866, 1992. PubMed: 1490876

Giacobbe RA, et al. Process for antifungal fermentation product. US Patent 4,968,608 dated Nov 6 1990

Fujimori F, Okuda T. Application of the random amplified polymorphic DNA using the polymerase chain reaction for efficient elimination of duplicate strains in microbial screening I. Fungi. J. Antibiot. 47: 173-182, 1994. PubMed: 8150713

Hensens OD, et al. Pneumocandins from Zalerion arboricola. III. Structure elucidation. J. Antibiot. 45: 1875-1885, 1992. PubMed: 1490878

Schmatz DM, et al. Pneumocandins from Zalerion arboricola. IV. Biological evaluation of natural and semisynthetic pneumocandins for activity against Pneumocystis carinii and Candida species. J. Antibiot. 45: 1886-1891, 1992. PubMed: 1490879

Adefarati AA, et al. Pneumocandins from Zalerion arboricola. V. Glutamic acid- and leucine-derived amino acids in pneumocandin A0 (L-671,329) and distinct origins of the substituted proline residues in pneumocandins A0 and B0. J. Antibiot. 45: 1953-1957, 1992. PubMed: 1362720

Bills GF, et al. Reclassification of a pneumocandin-producing anamorph, Glarea lozoyensis gen. et sp. nov., previously identified as Zalerion arboricola. Mycol. Res. 103: 179-192, 1999.

Lu P, et al. A gene (pks2) encoding a putative 6-methylsalicylic acid synthase from Glarea lozoyensis. Mol Genet Genomics 273: 207-216, 2005. PubMed: 15800788

Zhang A, et al. Efficient disruption of a polyketide synthase gene ( pks1) required for melanin synthesis through Agrobacterium-mediated transformation of Glarea lozoyensis. Mol Genet Genomics 268: 645-655, 2003. PubMed: 12589439

梅經理 17280875617 1438578920
胡經理 13345964880 2438244627
周經理 17757487661 1296385441
于經理 18067160830 2088210172
沈經理 19548299266 2662369050
李經理 13626845108 972239479
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