This is the first strain of this virus isolated and identified; it has been used since 1933 in the Public Health Service as the standard strain of this agent.
Armstrong E-350 strain can be used for immunizing guinea pigs.
This is the first strain of this virus isolated and identified; it has been used since 1933 in the Public Health Service as the standard strain of this agent.
Biosafety Level
3
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Isolation
clinical specimen - human
Isolation date: 1933
Isolated from monkeys initially inoculated with material from a human patient, St. Louis encephalitis epidemic of 1933
Product Format
frozen
Storage Conditions
-70°C or colder
Comments
Low virulence for GP when injected by s.c. route. This is the first strain of this virus isolated and identified; it has been used since 1933 in the Public Health Service as the standard strain of this agent.
LCM is highly infectious and may infect laboratory workers or invade animal colonies. See Hellman et al. (1975: Amer. J. Epidem. 101:103) for information on human infections. Armstrong E-350 strain can be used for immunizing guinea pigs.
Low virulence for GP when injected by s.c. route. This is the first strain of this virus isolated and identified; it has been used since 1933 in the Public Health Service as the standard strain of this agent.
Effect on Host
Yes, in vivo effects: dealth in suckling mice (i. c. inoculation)
death in mice;
Recommended Host
Saguinus oedipus
marmoset
Cebus sp.
capuchin monkey
mouse, i.c. inoculation
monkey; mouse; guinea pig
Growth Conditions
Incubation: 5-6 days
Name of Depositor
EH Lennette, R Emmons
Special Collection
ATCC
Source
clinical specimen - human
Isolation date: 1933
Isolated from monkeys initially inoculated with material from a human patient, St. Louis encephalitis epidemic of 1933
Year of Origin
1933
References
Armstrong C, Lillie, RD. Experimental lymphocytic choriomeningitis of monkeys and mice produced by a virus encountered in studies of the 1933 St. Louis encephalitis epidemic. Public Health Rep. 49: 1019-1027, 1934.
