| Insert |
DNA: genomic Insert lengths(kb): 2.200000047683716 Gene product: Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog(Harvey rat sarcoma virus oncogene) [HRAS] Alleles: c, s, , , F1, F2, F3, C1, F1, F2, F3, C1, H4, H4, H1, H2, H3, D1, D2, H1, H2, H3, D1, D2, C2, C2 |
| Comments |
Restriction digests analyzed on agarose gels give the following sizes (kb): EcoRI--6.6; EcoRI/BamHI--4.4, 2.2. This contains internal KpnI, AccI, SacI (2), SstII, BglI, SmaI, HindIII (2), PvuII, PstI, XbaI, BglII, and HincII sites. The viral sequences are in the AccI/PstI fragment. A 0.9 kb HindIII fragment was used as a probe in linkage studies on mouse chromosome 7. |
| References |
Saunders AM, Seldin MF. The syntenic relationship of proximal mouse chromosome 7 and the myotonic dystrophy gene region on human chromosome 19q. Genomics 6: 324-332, 1990. PubMed: 2307474
Kochevar DT, et al. Low level amplification of c-sis and c-myc in a spontaneous osteosarcoma model. Cancer Lett. 53: 213-222, 1990. PubMed: 2208081
Ellis RW, et al. The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. Nature 292: 506-511, 1981. PubMed: 6265801
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