| Comments |
Restriction digests of the clone give the following sizes (kb): PstI--3.8; BamHI, SalI, PvuII or HindIII--4.3. The insert has 5 internal PstI sites. Encodes amino acids 81-299 and contains the 158 bp 3' untranslated region and 44 bp poly(A). The genomic clone lambda APO-E (ATCC 57026, 57027) contains a 14 kb insert extending from 7 kb upstream to 5 kb downstream of the 2 kb EcoRI fragment containing sequences homologous this clone. |
| References |
Breslow JL, et al. Identification and DNA sequence of a human apolipoprotein E cDNA clone. J. Biol. Chem. 257: 14639-14641, 1982. PubMed: 6897404
Breslow JL, et al. Identification and DNA sequence of a human apolipoprotein E cDNA clone. J. Biol. Chem. 258: 14639-14641, 1983. PubMed: 6897404
Zannis VI, et al. Synthesis, intracellular processing, and signal peptide of human apolipoprotein E. J. Biol. Chem. 259: 5495-5499, 1984. PubMed: 6325438
Lusis AJ, et al. Regional mapping of human chromosome 19: organization of genes for plasma lipid transport (APOC1, -C2, and -E and LDLR) and the genes C3, PEPD, and GPI. Proc. Natl. Acad. Sci. USA 83: 3929-3933, 1986. PubMed: 3459164
|
