| Insert |
DNA: cDNA Insert lengths(kb): 0.7250000238418579 Tissue: breast adenocarcinoma MCF7 AdrR cell line Gene product: glutathione S-transferase pi [GST3] Alleles: B1, B2, A1, A2, B1, B2, A1, A2 |
| Comments |
Insert contains the following sites separated by (kb): EcoRI- 0.07- SphI- 0.11- HinfI- 0.025- RsaI- 0.185- SmaI, MspI- 0.07- BglII- 0.115- MspI- 0.035- RsaI- 0.05- HinfI- 0.065- EcoRI. Restriction digests of the clone give the following sizes (kb): EcoRI--2.6, 0.75; SmaI--2.9, 0.43; BglII--3.4; HinfI--1.0, 0.49, 0.42, 0.35, 0.32, 0.1; RsaI--1.4, 0.62, 0.45, 0.42, 0.32, 0.2. Contains the entire amino acid coding sequence and 17 bp of the 5' untranslated sequence. Enzyme(s) not detecting polymorphism: BamHI, BglII, HindIII, MspI, RsaI, SstI, TaqI, XbaI. |
| References |
Moscow JA, et al. Isolation of the human anionic glutathione S-transferase cDNA and the relation of its gene expression to estrogen-receptor content in primary breast cancer. Proc. Natl. Acad. Sci. USA 85: 6518-6522, 1988. PubMed: 2842775
Moscow JA, et al. Expression of anionic glutathione-S-transferase and P-glycoprotein genes in human tissues and tumors. Cancer Res. 49: 1422-1428, 1989. PubMed: 2466554
Morrow CS, et al. Structure of the human genomic glutathione S-transferase-pi gene. Gene 75: 3-11, 1989. PubMed: 2542132
Cheah KS, et al. A StuI RFLP in the human COL11A2 gene. Nucleic Acids Res. 18: 4964, 1990. PubMed: 1975680
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